When you say "DCC system" do you mean decoder or a complete control system?
I can't comment on sound decoders/systems as I haven't fited one to mine. I would imagine a QSI Quantum Aristo would be the obvious "plug and play" option for a combined sound and motor decoder, assuming an appropriate sound file is available?
If you go for the normal "plug and play" option of a Digitrax DG583AR decoder, there are do seem to be some minor annoyances with the directional lighting when using this decoder in this loco (due to the microcontroller chip used on the main board). I ended up doing some rewiring of the lighting to the DG583's auxiliary function output socket, bypassing the main board. I did write this up and post it, but it may have been on the old GSM site not here.
I'm sure some other folk have gone down the route of ripping out the existing board and wiring their own choice of decoder & sound.